Scientist - Investigative Toxicology

Cambridge, Massachusetts

This job has expired.

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2020, Eurofins generated total revenues of EUR € 5.4 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

The Global Investigative Toxicology team is a cross-functional team of scientists that aim to detect and de-risk toxicity in Client's portfolio to help make medicines safer and more effective. We are looking for a Research Associate Scientist to support these efforts across platforms and modalities. The Research Associate Scientist will contribute ideas and deliver decision-making data to inform project teams on improved efficacy and/or de-risking of potential toxicities.

  • Work as part of a global team of safety assessment scientists to detect and de-risk toxicities associated client's assets.
  • Design and implement early safety assessment screening strategies to enable the progression of optimized therapeutic candidates.
  • Conduct cell-based in vitro assays to characterize toxicities for medicines in discovery & development.
  • Develop novel in vitro model systems to assess safety risks associated client's assets.
  • Develop, design, execute, and interpret in vitro cell-based assays to characterize diverse mechanisms of toxicity.
  • Maintain cultures of immortalized tumor cell lines, primary cell types of various origin (lung, liver, kidney, intestine, pancreas, blood etc.) with primary focus being on primary CD34+ cells and differentiating CD34+ cells to various cell types.
  • Prepare experimental protocols, analyze experimental data, and present study results in team and department meetings.
  • Contribute ideas to drive innovation within investigative toxicology and with key collaborators (e.g. pharmacology, DMPK, bioinformatics).
  • Good documentation practices are required.

  • Ph.D. with 0-1 years or MS. with 3+ years or BS with 5+ years of experience in biology, biochemistry, pharmacology, or a related discipline.
  • Expert with standard aseptic cell culture technique, including experience culturing various tumor cell lines and primary cells. Experience with culturing and differentiating CD34+ cells is a plus.
  • Broad experience with cell-based functional assays. Experience with cell transfection/transduction, imaging, and flow cytometry is a plus.
  • Basic experience with molecular biology techniques including RNA/DNA extraction, qPCR, western blot
  • Experience working in a matrixed team environment at a pharmaceutical company and/or CRO.
  • Broad scientific knowledge in hematology, immunology, and pharmacology.
  • Self-motivated with strong time management and organizational skills.

Additional Information

Position is full-time, Monday - Friday 8:00am - 5:00pm.Candidates currently living within a commutable distance of Cambridge, MAare encouraged to apply.Excellent full time benefits including comprehensive medical coverage, dental, and vision options.
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

Eurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

This job has expired.

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