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About Astellas Gene Therapies
Astellas Gene Therapies is an Astellas Center of Excellence developing genetic medicines for patients with rare, life-threatening diseases. Based on our innovative approach to developing genetic medicines, as well as our industry-leading internal manufacturing capability and expertise, we have become the Astellas Center of Excellence for their newly-created Genetic Regulation Focus Area. We are currently exploring three gene therapy modalities: gene replacement, exon skipping gene therapy, and vectorized RNA knockdown, with plans to expand our focus and geographic reach under Astellas. We are based in San Francisco, with manufacturing and laboratory facilities in South San Francisco and Sanford, North Carolina. For more information, please visit our website: www.astellasgenetherapies.com
About Astellas
Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are promoting the Focus Area Approach that is designed to identify opportunities for the continuous creation of new drugs to address diseases with high unmet medical needs by focusing on Biology and Modality. Furthermore, we are also looking beyond our foundational Rx focus to create Rx+® healthcare solutions that combine our expertise and knowledge with cutting-edge technology in different fields of external partners. Through these efforts, Astellas stands on the forefront of healthcare change to turn innovative science into value for patients. For more information, please visit our website at https://www.astellas.com/en.
Our Values:
- Be BOLD (Find a Way)
- Care Deeply - for our patients, each other and our work
- #GSD (Get Stuff Done)
What is the catalyst for you in your professional career? Are you ready to be a part of a bold, innovative company, to make a change and to make a difference? Listed below is a current opening for a smart, driven, experienced, and just plain nice individual who wants to join us and be a part of our journey.
The Role
The primary responsibilities of the Biophysical Characterization Research Associate will include performing analytical method development and testing samples using HPLC, capillary electrophoresis and other analytical tools; contributing to design and performing experiments with supervision as needed, for completing tasks within assigned time frames and for maintaining a well-documented record of activities in batch records and lab notebook. The position level will be commensurate with education and experience level. Additionally, the role includes regularly summarizing experiments in lab meetings and assisting in generating reports. This role will be at our South San Francisco location.
Primary Responsibilities
- Conducting experiments to characterize adeno associated viral nanoparticles for gene therapy products
- Developing and running assays for particle/protein/DNA biophysical assays (SDS-PAGE, DLS, Western Blot, Light Obscuration, RP, SE - HPLC methods, AUC, Capillary Electrophoresis)
- Developing additional assays as needed for process development and formulation studies
- Developing new characterization tools or following SOPs and running experiments according to guidelines
- Assisting in formulation and stability study set up, monitoring and analyzing data using statistical methods
- Assisting in writing, reviewing, and editing experimental procedures and reports
- Maintaining accurate records of all analytical development activities
- Analyzing and determining the applicability of laboratory data to draw conclusions and to make appropriate recommendations
This job has expired.
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