Post Doctoral Fellow - Microbiology, Immunology and Cell Biology
West Virginia University Research Corporation

Morgantown, West Virginia

This job has expired.


Description

West Virginia University Research Corporation is seeking applications for a Post Doctoral Fellow in the Department of Microbiology, Immunology and Cell Biology 

About the Opportunity

We are hiring a postdoctoral trainee to participate on an R01 funded vaccine development project for Lyme disease. Our team uses in vitro and in vivo animal models, cell and molecular biology techniques, next-generation sequencing, and highly complex immunological assays to determine vaccine efficacy. 

The current project focuses on the development of mRNA and peptide-based vaccine to protect against Lyme disease. This includes:

  • Performing antigen identification using molecular modeling, immunogenicity studies, and in vivo gene expression analysis 
  • Testing peptide vaccine efficacy using B. burgdorferi murine models of vaccination and challenge
  • Characterizing T and B cell responses during B. burgdorferi vaccination and challenge
  • Work on novel mRNA vaccines in collaboration with industry partners associated with the WVU Vaccine Development center 
At WVU Research Corporation, we strongly believe in work-life balance and keeping time for things we love outside our work. WVU Research Corporation offers a comprehensive benefits package with a variety of options to suit your needs:
•    13 paid holidays (staff holiday calendar)
•    PTO
•    403(b) retirement savings with a fully vested 3% employee contribution match, (Employees have the option of contributing an additional 1-3% of their earnings to the plan, which is also matched by the WVURC)
•    A range of health insurance and various other benefits
•    Dependent Education Scholarship
•    WVU Perks
•    And More!!

What you’ll do:
  • Conducting Molecular Biology Techniques. 
  • Conducting vaccinology research.
  • Conducting animal challenge experiments.
  • Conducting Immunological assays such as ELISA, and Flow Cytometry. 
  • Supporting routine laboratory operation, such as preparation of reagents and maintenance of animal colonies, cleaning and organization of the laboratory
  • Assisting graduate and undergraduate students.
  • Preparing manuscript and data presentations.
  • Ordering of necessary materials and resources, scheduling/coordination, culture of bacteria, challenge, and evaluation of vaccine correlates of protection.
  • Infection, monitoring, and data collection of animal models of infection in relation to vaccination. 
  • The candidate will develop new laboratory protocols and methods. 
  • Attend research conferences and read scientific literature to keep abreast of technological advances and current research findings. 
  • Perform laboratory and field experiment activities according to protocol. Assure compliance with research protocols and safety requirements. 
  • Assist with undergraduate and graduate researchers training
  • Assist with the completion of experiments, maintain lab equipment, keep accurate inventory of lab assets, and monitor and assure proper use and conditions of lab equipment. 
  • Write and present research/study status reports for review and use of the Principal Investigator. 
  • Prepare results of experimental findings for presentation to colleagues and the sponsor; at professional/technical conferences; and/or, for publication in scientific journals, as directed.
 

Qualifications

  • PhD in Microbiology or related field with prior expertise with working with B. burgdorferi animal models. Candidates from related disciplines with strong immunology background are also encouraged to apply.
  • Minimum 0-5+ years' of experience performing related in vitro and in vivo experiments, culturing of bacteria, cellular and molecular research.
  • Knowledge in working with spirochetes, and in particular B. burgdorferi
  • Knowledge in animal models of B. burgdorferi
  • Skilled in Molecular Biology
  • Skilled in cell culture techniques
  • Skilled in microbiological and immunological techniques.
  • Ability to perform vaccine efficacy studies
  • Ability to maintain animal colonies.
  • Skilled to use scientific methods and rules to solve problems.
  • Skilled at operating laboratory instrumentation.
  • Skilled to identify complex problems and reviewing related information to develop and evaluate options and implement solutions.
  • Ability to maintain attention to detail.
  • Basic Knowledge of cell biology, molecular biology, and biology.
  • Working knowledge of using laboratory equipment.
  • Knowledge of laboratory protocols, and procedures.
  • Knowledge of animal organisms, their tissues, cells, functions, environment.
  • Knowledge of uses of chemicals and their interactions, danger signs, production techniques, and disposal methods.
  • Ability to gather, understand and implement technical protocols.
  • Ability to read and interpret documents such as safety rules, operating and maintenance instructions, and procedure manuals.
  • Ability to write routine reports and correspondence
  • Ability to perform effectively under conditions of fluctuating workload.
  • Ability to work independently to complete assigned projects


About WVU

Due to the nature of this job, it may or may not require Medical Monitoring


This job has expired.

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